abstract：Importance:Incorporating combination vaccines, such as the measles-mumps-rubella-varicella (MMRV) vaccine, into immunization schedules should be evaluated from a benefit-risk perspective. Use of MMRV vaccine poses challenges due to a recognized increased risk of febrile seizures (FSs) when used as the first dose in the...

journal_title：JAMA pediatrics

authors： Macartney K,Gidding HF,Trinh L,Wang H,Dey A,Hull B,Orr K,McRae J,Richmond P,Gold M,Crawford N,Kynaston JA,McIntyre P,Wood N,Paediatric Active Enhanced Disease Surveillance Network.

更新日期：2017-10-01 00:00:00

abstract：Importance:Inflammatory bowel diseases (IBD), such as Crohn disease and ulcerative colitis, are chronic relapsing conditions that affect a growing number of children worldwide. The pathogenesis of these disorders is complex and thought to be mediated by the interplay between genetic susceptibility, microbial dysbiosis,...

journal_title：JAMA pediatrics

authors： Shouval DS,Rufo PA

更新日期：2017-10-01 00:00:00

abstract：Importance:Caffeine citrate therapy for apnea of prematurity reduces the rates of bronchopulmonary dysplasia, severe retinopathy, and neurodevelopmental disability at 18 months and may improve motor function at 5 years. Objective:To evaluate whether neonatal caffeine therapy is associated with improved functional outc...

journal_title：JAMA pediatrics

authors： Schmidt B,Roberts RS,Anderson PJ,Asztalos EV,Costantini L,Davis PG,Dewey D,D'Ilario J,Doyle LW,Grunau RE,Moddemann D,Nelson H,Ohlsson A,Solimano A,Tin W,Caffeine for Apnea of Prematurity (CAP) Trial Group.

更新日期：2017-06-01 00:00:00

abstract：Importance:Zika virus infection can be prenatally passed from a pregnant woman to her fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause of microcephaly and serious brain anomalies, but the full spectrum of anomalies has not been delineated. To inform pediatric clinicians ...

journal_title：JAMA pediatrics

authors： Moore CA,Staples JE,Dobyns WB,Pessoa A,Ventura CV,Fonseca EB,Ribeiro EM,Ventura LO,Neto NN,Arena JF,Rasmussen SA

更新日期：2017-03-01 00:00:00

abstract：Importance:Sudden infant death syndrome remains the leading cause of death in infants aged 1 month to 1 year in the United States. Observations:While its exact cause is unknown, sudden infant death syndrome is believed to be multifactorial, ie, occurs in infants with underlying biological vulnerability who experience ...

journal_title：JAMA pediatrics

authors： Carlin RF,Moon RY

更新日期：2017-02-01 00:00:00

abstract：Importance:Home aeroallergen exposure is associated with increased asthma morbidity in children, yet little is known about the contribution of school aeroallergen exposures to such morbidity. Objective:To evaluate the effect of school-specific aeroallergen exposures on asthma morbidity among students, adjusting for ho...

journal_title：JAMA pediatrics

authors： Sheehan WJ,Permaul P,Petty CR,Coull BA,Baxi SN,Gaffin JM,Lai PS,Gold DR,Phipatanakul W

更新日期：2017-01-01 00:00:00

abstract：Importance:The associations between hydration status, intravenous fluid administration, and outcomes of patients infected with Shiga toxin-producing Escherichia coli (STEC) remain unclear. Objective:To determine the relationship between hydration status, the development and severity of hemolytic uremic syndrome (HUS),...

journal_title：JAMA pediatrics

authors： Grisaru S,Xie J,Samuel S,Hartling L,Tarr PI,Schnadower D,Freedman SB,Alberta Provincial Pediatric Enteric Infection Team.

更新日期：2017-01-01 00:00:00

abstract：Importance:This study was designed to determine whether a preventive intervention focused on enhancing supportive parenting could ameliorate the association between exposure to poverty and brain development in low socioeconomic status African American individuals from the rural South. Objective:To determine whether pa...

journal_title：JAMA pediatrics

authors： Brody GH,Gray JC,Yu T,Barton AW,Beach SR,Galván A,MacKillop J,Windle M,Chen E,Miller GE,Sweet LH

更新日期：2017-01-01 00:00:00

abstract：Importance:Sleep is vital to children's biopsychosocial development. Inadequate sleep quantity and quality is a public health concern with an array of detrimental health outcomes. Portable mobile and media devices have become a ubiquitous part of children's lives and may affect their sleep duration and quality. Object...

journal_title：JAMA pediatrics

authors： Carter B,Rees P,Hale L,Bhattacharjee D,Paradkar MS

更新日期：2016-12-01 00:00:00

abstract：Importance:Parents regularly express concern about long-term health outcomes for children who are born with an oral cleft. Objective:To assess whether oral clefts affect the health and ability to work of young adults. Design, Setting, and Participants:A population-based cohort study was conducted on all individuals b...

journal_title：JAMA pediatrics

authors： Berg E,Haaland ØA,Feragen KB,Filip C,Vindenes HA,Moster D,Lie RT,Sivertsen Å

更新日期：2016-11-01 00:00:00

abstract：Importance:Infantile beriberi, a potentially fatal disease caused by thiamine deficiency, remains a public health concern in Cambodia and regions where thiamine-poor white rice is a staple food. Low maternal thiamine intake reduces breast milk thiamine concentrations, placing breastfed infants at risk of beriberi. Obj...

journal_title：JAMA pediatrics

authors： Whitfield KC,Karakochuk CD,Kroeun H,Hampel D,Sokhoing L,Chan BB,Borath M,Sophonneary P,McLean J,Talukder A,Lynd LD,Li-Chan EC,Kitts DD,Allen LH,Green TJ

更新日期：2016-10-03 00:00:00

abstract：IMPORTANCE:As of 2015, almost half of US states allow medical marijuana, and 4 states allow recreational marijuana. To our knowledge, the effect of recreational marijuana on the pediatric population has not been evaluated. OBJECTIVE:To compare the incidence of pediatric marijuana exposures evaluated at a children's ho...

journal_title：JAMA pediatrics

authors： Wang GS,Le Lait MC,Deakyne SJ,Bronstein AC,Bajaj L,Roosevelt G

更新日期：2016-09-06 00:00:00

abstract：IMPORTANCE:Late-term gestation (defined as the 41st week of pregnancy) is associated with increased risk of perinatal health complications. It is not known to what extent late-term gestation is associated with long-term cognitive and physical outcomes. Information about long-term outcomes may influence physician and pa...

journal_title：JAMA pediatrics

authors： Figlio DN,Guryan J,Karbownik K,Roth J

更新日期：2016-08-01 00:00:00

abstract：IMPORTANCE:Smaller cerebral volumes at hospital discharge in very preterm (VPT) infants are associated with poor neurobehavioral outcomes. Brain growth from the newborn period to middle childhood has not been explored because longitudinal data have been lacking. OBJECTIVES:To examine the pattern of growth of cerebral ...

journal_title：JAMA pediatrics

authors： Monson BB,Anderson PJ,Matthews LG,Neil JJ,Kapur K,Cheong JL,Doyle LW,Thompson DK,Inder TE

更新日期：2016-08-01 00:00:00

abstract：IMPORTANCE:Although data obtained from regional trauma systems demonstrate improved outcomes for children treated at pediatric trauma centers (PTCs) compared with those treated at adult trauma centers (ATCs), differences in mortality have not been consistently observed for adolescents. Because trauma is the leading cau...

journal_title：JAMA pediatrics

authors： Webman RB,Carter EA,Mittal S,Wang J,Sathya C,Nathens AB,Nance ML,Madigan D,Burd RS

更新日期：2016-08-01 00:00:00

abstract：IMPORTANCE:The American Academy of Pediatrics treatment recommendations for neonatal jaundice are based on age-specific total serum bilirubin (TSB) levels. In May 2012, Ortho Clinical Diagnostics adjusted the calibrator values for Vitros Chemistry Products BuBc Slides (Ortho Clinical Diagnostics), a widely used method ...

journal_title：JAMA pediatrics

authors： Kuzniewicz MW,Greene DN,Walsh EM,McCulloch CE,Newman TB

更新日期：2016-06-01 00:00:00

abstract：IMPORTANCE:Although cancer remains the most common cause of disease-related death in adolescents and young adults (AYAs) in high-income countries, their overall survival rates continue to increase and now exceed 80% at 5 years in several high-income countries. This has been accomplished through progressive improvements...

journal_title：JAMA pediatrics

authors： Barr RD,Ferrari A,Ries L,Whelan J,Bleyer WA

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:Current acellular pertussis vaccines may not protect against transmission of Bordetella pertussis. OBJECTIVE:To assess whether a priming dose of whole-cell pertussis (wP) vaccine is cost-effective at reducing pertussis infection in infants. DESIGN, SETTING, AND PARTICIPANTS:Mathematical model of pertussis ...

journal_title：JAMA pediatrics

authors： DeAngelis H,Scarpino SV,Fitzpatrick MC,Galvani AP,Althouse BM

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:The quadrivalent human papillomavirus (HPV) vaccine was licensed for use in 9- through 26-year-old females in 2006. Postlicensure studies in Australia, Denmark, and Canada have demonstrated vaccine effectiveness against abnormal cervical cytology results. However, there are limited data describing postlicens...

journal_title：JAMA pediatrics

authors： Hofstetter AM,Ompad DC,Stockwell MS,Rosenthal SL,Soren K

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:Rape on college campuses has been addressed recently by a presidential proclamation, federal legislation, advocacy groups, and popular media. Many initiatives assume that most college men who perpetrate rape are serial rapists. The scientific foundation for this perspective is surprisingly limited. OBJECTIV...

journal_title：JAMA pediatrics

authors： Swartout KM,Koss MP,White JW,Thompson MP,Abbey A,Bellis AL

更新日期：2015-12-01 00:00:00

abstract：IMPORTANCE:Early adversity is an important risk factor that relates to internalizing symptoms and altered brain structure. OBJECTIVE:To assess the direct effects of early adversity and child internalizing symptoms (ie, depression, anxiety) on cortical gray matter (GM) volume, as well as the extent to which early adver...

journal_title：JAMA pediatrics

authors： Jensen SK,Dickie EW,Schwartz DH,Evans CJ,Dumontheil I,Paus T,Barker ED

更新日期：2015-10-01 00:00:00

abstract：IMPORTANCE:Obesity is associated with chronic musculoskeletal pain and is a risk factor for disability and osteoarthritis. OBJECTIVES:To describe the prevalence, sites, and intensity of musculoskeletal pain in adolescents with severe obesity; to evaluate associations between musculoskeletal pain and self-reported phys...

journal_title：JAMA pediatrics

authors： Bout-Tabaku S,Michalsky MP,Jenkins TM,Baughcum A,Zeller MH,Brandt ML,Courcoulas A,Buncher R,Helmrath M,Harmon CM,Chen MK,Inge TH

更新日期：2015-06-01 00:00:00

abstract：:Addressing the childhood obesity epidemic continues to be a challenge. Given that once obesity develops it is likely to persist, there has been an increasing focus on prevention at earlier stages of the life course. Research to develop and implement effective prevention and intervention strategies in the first 2 years...

journal_title：JAMA pediatrics

authors： Lumeng JC,Taveras EM,Birch L,Yanovski SZ

更新日期：2015-05-01 00:00:00

abstract：IMPORTANCE:Little is known about the long-term effect of a chef-enhanced menu on healthier food selection and consumption in school lunchrooms. In addition, it remains unclear if extended exposure to other strategies to promote healthier foods (eg, choice architecture) also improves food selection or consumption. OBJE...

journal_title：JAMA pediatrics

authors： Cohen JF,Richardson SA,Cluggish SA,Parker E,Catalano PJ,Rimm EB

更新日期：2015-05-01 00:00:00

abstract：IMPORTANCE:Most patients with asthma take fewer than half of prescribed doses of controller medication. Interventions to improve adherence have typically been costly, impractical, and at best only minimally successful. OBJECTIVE:To test a speech recognition (SR) intervention to improve adherence to pediatric asthma co...

journal_title：JAMA pediatrics

authors： Bender BG,Cvietusa PJ,Goodrich GK,Lowe R,Nuanes HA,Rand C,Shetterly S,Tacinas C,Vollmer WM,Wagner N,Wamboldt FS,Xu S,Magid DJ

更新日期：2015-04-01 00:00:00

abstract：IMPORTANCE:Neonatal hypothermia has been associated with higher mortality and morbidity; therefore, thermal control following delivery is an essential part of neonatal care. Identifying the ideal body temperature in preterm neonates in the first few hours of life may be helpful to reduce the risk for adverse outcomes. ...

journal_title：JAMA pediatrics

authors： Lyu Y,Shah PS,Ye XY,Warre R,Piedboeuf B,Deshpandey A,Dunn M,Lee SK,Canadian Neonatal Network.

更新日期：2015-04-01 00:00:00

abstract：IMPORTANCE:Efforts to transform primary care through the medical home model may have limited effectiveness if they do not incorporate families' preferences for different primary care services. OBJECTIVE:To assess parents' relative preferences for different categories of enhanced access services in primary care. DESIG...

journal_title：JAMA pediatrics

authors： Zickafoose JS,DeCamp LR,Prosser LA

更新日期：2015-04-01 00:00:00

abstract：IMPORTANCE:Reminder/recall notifications used by primary care practices increase the rates of childhood immunizations, but fewer than 20% of primary care practitioners nationally deliver such reminders. A reminder/recall notification conducted centrally by health departments in collaboration with primary care practices...

journal_title：JAMA pediatrics

authors： Kempe A,Saville AW,Dickinson LM,Beaty B,Eisert S,Gurfinkel D,Brewer S,Shull H,Herrero D,Herlihy R

更新日期：2015-04-01 00:00:00

abstract：IMPORTANCE:Exchange transfusion is recommended for newborns with total serum bilirubin (TSB) levels thought to place them at risk for cerebral palsy (CP). However, the excess risk for CP among these infants is unknown. OBJECTIVE:To quantify the risks for CP and CP consistent with kernicterus that are associated with h...

journal_title：JAMA pediatrics

authors： Wu YW,Kuzniewicz MW,Wickremasinghe AC,Walsh EM,Wi S,McCulloch CE,Newman TB

更新日期：2015-03-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and is considered the most common form of chronic liver disease in children. Several factors contribute to NAFLD development, including race/ethnicity, genetic factors, environmental exposures, and alterations in the gut mi...

journal_title：JAMA pediatrics

authors： Nobili V,Alkhouri N,Alisi A,Della Corte C,Fitzpatrick E,Raponi M,Dhawan A

更新日期：2015-02-01 00:00:00

abstract：IMPORTANCE:Most studies examining the association of prenatal antiretroviral (ARV) exposures with congenital anomalies (CAs) in children born to human immunodeficiency virus (HIV)-infected women have been reassuring, but some evidence suggests an increased risk with specific ARV agents. OBJECTIVE:To evaluate the assoc...

journal_title：JAMA pediatrics

authors： Williams PL,Crain MJ,Yildirim C,Hazra R,Van Dyke RB,Rich K,Read JS,Stuard E,Rathore M,Mendez HA,Watts DH,Pediatric HIV\/AIDS Cohort Study.

更新日期：2015-01-01 00:00:00

abstract：IMPORTANCE:There has been a significant expansion in the number of low-level and midlevel neonatal intensive care units (NICUs) in recent decades. Infants with necrotizing enterocolitis represent a high-risk subgroup of the very low-birth-weight (VLBW) (<1500 g) population that would benefit from focused regionalizatio...

journal_title：JAMA pediatrics

authors： Kastenberg ZJ,Lee HC,Profit J,Gould JB,Sylvester KG

更新日期：2015-01-01 00:00:00

abstract：IMPORTANCE:Short-term impacts of breakfast consumption on diet quality and cognitive functioning have been reported, but more evidence is needed to draw causal inferences about long-term impacts of school breakfast on indicators of school engagement and academic achievement. OBJECTIVE:To estimate the impact of a Break...

journal_title：JAMA pediatrics

authors： Anzman-Frasca S,Djang HC,Halmo MM,Dolan PR,Economos CD

更新日期：2015-01-01 00:00:00

abstract：IMPORTANCE:It is unclear whether the benefits of tobacco control policies extend to pregnant women and infants, especially among racial/ethnic minority and low socioeconomic populations that are at highest risk for adverse birth outcomes. OBJECTIVE:To examine the associations of state cigarette taxes and the enactment...

journal_title：JAMA pediatrics

authors： Hawkins SS,Baum CF,Oken E,Gillman MW

更新日期：2014-11-01 00:00:00

abstract：IMPORTANCE:Behavioral change interventions have demonstrated short-term efficacy in reducing sexually transmitted infection (STI)/human immunodeficiency virus (HIV) risk behaviors; however, few have demonstrated long-term efficacy. OBJECTIVE:To evaluate the efficacy of a telephone counseling prevention maintenance int...

journal_title：JAMA pediatrics

authors： DiClemente RJ,Wingood GM,Sales JM,Brown JL,Rose ES,Davis TL,Lang DL,Caliendo A,Hardin JW

更新日期：2014-10-01 00:00:00

abstract：IMPORTANCE:Histamine-2 receptor antagonists (H2RAs) are frequently used in the treatment of gastroesophageal reflux disease (GERD) in children; however, their efficacy and safety is questionable. OBJECTIVE:To systematically review the literature to assess the efficacy and safety of H2RAs in pediatric GERD. EVIDENCE R...

journal_title：JAMA pediatrics

authors： van der Pol R,Langendam M,Benninga M,van Wijk M,Tabbers M

更新日期：2014-10-01 00:00:00

abstract：IMPORTANCE:In recent years, across the United States, many school districts have cut on-site delivery of health services by eliminating or reducing services provided by qualified school nurses. Providing cost-benefit information will help policy makers and decision makers better understand the value of school nursing s...

journal_title：JAMA pediatrics

authors： Wang LY,Vernon-Smiley M,Gapinski MA,Desisto M,Maughan E,Sheetz A

更新日期：2014-07-01 00:00:00

abstract：IMPORTANCE:Peer victimization is related to an increased chance of suicidal ideation and suicide attempts among children and adolescents. OBJECTIVE To examine the relationship between peer victimization and suicidal ideation or suicide attempts using meta-analysis. DATA SOURCES Ovid MEDLINE, PsycINFO, and Web of Scienc...

journal_title：JAMA pediatrics

authors： van Geel M,Vedder P,Tanilon J

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Obesity affects health in children and adolescents. Television viewing is an established risk factor for obesity in youth. No prospective study has assessed whether a bedroom television confers an additional risk for obesity in youth. OBJECTIVE:To assess the prospective association between the presence of a...

journal_title：JAMA pediatrics

authors： Gilbert-Diamond D,Li Z,Adachi-Mejia AM,McClure AC,Sargent JD

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Chronic fatigue syndrome (CFS) is a disabling condition with unknown disease mechanisms and few treatment options. OBJECTIVE:To explore the pathophysiology of CFS and assess clonidine hydrochloride pharmacotherapy in adolescents with CFS by using a hypothesis that patients with CFS have enhanced sympathetic...

journal_title：JAMA pediatrics

authors： Sulheim D,Fagermoen E,Winger A,Andersen AM,Godang K,Müller F,Rowe PC,Saul JP,Skovlund E,Øie MG,Wyller VB

更新日期：2014-04-01 00:00:00